If you aren't seeing any effect then it's probably time to go back to the doctor. Perhaps your symptoms aren't due to reflux. In fact, the doctor that I saw in the fall told me that I did not need to be scoped if the medicine did the trick but if it didn't he wanted to do the endoscopy to see what was going on.
I've read that it can take two full weeks to see the full effect due to the healing that may need to occur but by 6 days you should have at least some improvement.
Omeprazole usually starts to be most effective after a few days. If you have had heartburn for a while, it may have caused some inflammation (esophagitis) making it more sensitive to heartburn. This should calm down in a few days.
What strength omeprazole are you on? 20mg is the normal maintenance dose though 40mg is more often prescribed initially for a few weeks. It may be you need a stronger prescription. Discuss this with your doctor.
Meanwhile, help yourself by trying to determine what your trigger foods are that are causing your heartburn by keeping a food diary. Common trigger foods include coffee, chocolate, citrus fruit, fatty foods, spicy food. But we are all different and not everyone reacts similarly to the same foods.
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