I am just wondering if it is possible to have an intolerance to citric acid? I was diagnosed with GERD a few years ago after having recurring bouts of severe acid reflux. At the time I had tried treating it with Tums, which I found to only worsen my symptoms and could not determine any OTC or Rx medication to help (I tried just about everything). Over the years I started to notice that orange juice was the worst for making my GERD act up. I could have one glass of orange juice and the next day I would feel like my stomach was on fire and I would develop a sore throat and ulcers in my mouth. The same would happen if I ate an orange or a grapefruit but I never was much of a citrus fruit-eater so it took me a long time to notice the connection. Ever since noticing this, I have pretty much stopped consuming citrus all together, and actually my acid reflux hasn't been a major problem. Despite the fact that I am always stressed (generalized anxiety disorder), drink strong coffee regularly, and can generally eat spicy sauces without difficulty, my GERD symptoms have almost entirely disappeared. (I still have mild symptoms sometimes, but nothing really terrible or long-lasting.) The only thing that is different is that I no longer eat citrus fruit. Has anyone ever heard of such a thing happening before?