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I have been taking Nexium at night and it worked extremely well. Recently, a doctor told me that I should take it in the mornings half hour to an hour before breakfast. It does not work as well as at night for me. When I take it in the morning it seems to trigger a desire to have a bowel movement. Also when I take it at night it seems to be more effective preventing burping at night. I am looking for answers regarding the best time to take it myself.