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jblack, Lowered sex drive is not listed in the side effects of Prilosec in our drug information guide. Are you taking any other medications? You may want to consider these as a possible source of the change. It is possible that Prilosec is not the best option for you. You may want to discuss other medication options with your doctor. For more information on other acid reflux medications, click here. Has anyone taking Prilosex experienced the same thing?

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