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Hi Sherry, You can read about Nexium here in the quick facts. Dr Todd Eisner addressed the dosage time in this answer to a question. You can read the entire posting here, but Dr Eisner said: "Question #4: If a patient forgets to take acid reflux medication one hour before a meal as prescribed, should the patient skip the dose? Dr. Eisner: Depending on the medication, taking it at anytime still would be beneficial. You should check with your doctor's office to see what is recommended." Hope this helps. Take care and stay in touch!Vicki M

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