In the studies the FDA used to look to determine the risk, 75% of patients who had low blood levels of magnesium...
Dangers Of Long Term Use Of Proton Pump Inhibitors
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The FDA recently released a report warning consumers that long term (greater than one year) use of Proton Pump Inhibitors leads to risk of low magnesium blood levels. This condition is known as hypomagnesemia. Low levels of magnesium in the blood can lead to muscle spasm, irregular heartbeat, or seizures but you can have low blood magnesium levels and not have these symptoms.
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