Barr Labs recently gained FDA approval for their generic version of Shire's Adderall XR. It is called Amphetamine Salts ER. My son was on the 10 mg Adderall XR with good results. We started on the generic and boy did things go down hill and fast. Extremely long temper tantrums, little focus, very alarming unsafe behaviors (running into the street) and extrememly oppositional. That was Friday, Saturday and Sunday. I dug in the bottle to see if we had any of the Addrall on Monday and he was a totally different child, back to his normal self. I forgot about it on Tuesday, he was impossible to get to sleep and extremely oppositional. Wednesday he unbuckled himself from his car seat and opened the side door of the van while we were driving home from day care. He was laughing histerically and saying he wanted to die and to kill me. He is 6. Talk about scary. I finally got him back in his car seat an managed to get most of the way before he popped out of his car seat again. Found another Addrall XR this morning and again a totally different child. Well mannered, very loving. Totally weird. I called the pharmacist this evening and asked them to take back the generic. I also asked them to file a product complaint. Didn't have much luck with that, but will bring it up to the psychiatrist when we see her. I just wanted to pass along my experiences so that others are aware of potential issues. Hopefully I spelled most things correctly.