You may have heard rumors that there is a shortage of the opioid pain reliever oxycodone . Or you may have tried to fill your oxycodone prescription only to be told that your pharmacy doesn't have any and doesn't know when they will be getting more. There have been at least two significant recalls of instant release oxycodone in the past few months and the two drug manufacturers involved have completely stopped production of it (as well as a number of other medications) due to quality control issues. Because of its abuse potential, oxycodone is highly regulated and the government only allows each manufacturer to make a specified amount each year. Therefore, other manufacturers cannot just increase their production to make up for the two companies who have stopped production. The shortage seems to affect some parts of the country worse than others, but as the shortage continues the number of areas affected are growing. It largely depends on which manufactur...
It's not unusual for people living with chronic pain to also be dealing with some depression and/or anxiety . But if you're taking an opioid like oxycodone for the pain and also taking an herbal supplement containing St. John's Wort, you may unknowingly be reducing the effectiveness of your pain medication. A small study in Finland found that when St. John's Wort and oxycodone were taken together, the plasma concentration of oxycodone decreased by 50 percent and its half-life (the time it takes for half the drug to be elimitated from the body) was shortened by 27 percent. The reason for the significant decrease in oxycodone's effectiveness may lie in the fact that St. John’s wort is a well-known to induce CYP450 liver enzymes, which play an important role in the metabolism of many opioids. Although oxycodone was the only opioid tested, it would be logical to think that other opioids which are metabolized through the CYP450 pathways might be similarly...
Generic Name: OXYCODONE/ACETAMINOPHEN - ORAL Pronounced: (OX-i-KOE-done/a-SEET-a-MIN-oh-fen) Oxycodone-Acetaminophen Oral Uses
This combination medication is used to help relieve
moderate to severe pain. It contains a narcotic pain reliever (oxycodone) and a
non-narcotic pain reliever (acetaminophen). Oxycodone works in the brain to
change how your body feels and responds to pain. Acetaminophen can also reduce
How To Use Oxycodone-Acetaminophen Oral
See also Warning section.
Take this medication by mouth as directed by your doctor.
You may take this drug with or without food. If you have nausea, it may help to
take this drug with food. Ask your doctor or pharmacist about other ways to
decrease nausea (such as lying down for 1 to 2 hours with as little head
movement as possible).
If you are using a liquid form of this medication, use a
medication measuring device to carefully measure the prescribed dose. Do not
use a ho...
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