Thank you for your question and welcome to ADHDCentral.com.   I am sorry your brother is having such a difficult time. Has your brother been tested for possible learning disabilities? There is a high incident rate between ADHD and learning disabilities and this may be a reason your brother dislikes school so much.   I am not a medical professional and would not be able to give you medical advice. However, it is always important to be sure you have an accurate diagnosis, especially if you are finding that treatment is not working. You may want to suggest your brother have a complete evaluation to make sure you are working with an accurate diagnosis.   I am giving you some links to articles that may be helpful:   12 Things High School Students with ADHD Want Teachers to Know   ADHD and Learning Disabilities   Study Skills for High School Students with ADHD   Learning Styles   Co-Existing Conditions   The Importance of an Accurate Diagnosis   I hope this helps   Eileen