Hi ocharlotte,

Thank you for your question! I'm not exactly sure what you're asking, but I seem to think that you're asking if there is a drug interaction between the aspirin, Xanax, and Depakote. There is the possibility of an interaction between the aspirin and Depakote, but if your mother is taking the same dose of aspirin every day she should be okay. The aspirin can cause the Depakote to be absorbed differently in the body, but that would only be a problem if she takes aspirin irregularly (like for a headache once a week). Otherwise, the combination of the three dose not present a problem. However, with the list of problems that you mentioned, your mother is probably on several other medications, and I can't say without knowing what they are whether the aspirin, Xanax, and Depakote interacts with any of those.

Best of luck,

Casey