Hello there   Health Central has a good site for Menopause that you might want to visit by following this link.   In researching your question it does seem that this medication can be used for hot flashes.   Here is one such article on this topic and here is some of what it tells us:    "Oral and transdermal formulations of clonidine are moderately effective in reducing hot flashes. Results of studies evaluating venlafaxine, paroxetine, and gabapentin suggest greater reductions in hot-flash frequency and severity compared with those of clonidine. Fluoxetine appears to display a modest benefit compared with paroxetine, although no comparative trials have been conducted."   I hope this helps some and thank you for your question!