Can Depakote Cause Birth Defects?

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Valproic acid, brand names Depakene and Depakote, is one of the few medications approved by the FDA for Migraine prevention.

Taking valproic acid during the first trimester of pregnancy has been associated with an increased risk of spina bifida. A study published in the June, 2010, issue of the New England Journal of medicine now associates it with other birth defects.

Study methods:

  • Researchers combined the data from eight previously published studies that included 1,565 pregnancies...
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