Your life isn't working right. You have a lot to feel depressed or agitated about. You see a general practitioner or psychiatrist, who prescribes an antidepressant for your depression. An antidepressant tends to be the default first option for those who tend to feel out of sorts.

But what if the antidepressant doesn't work?

In the event of one failed or partially successful trial on an antidepressant, the American Psychiatric Association in its 2000 Practice Guideline for treating depression...