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Wednesday, November, 11, 2009
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Great News: Little Evidence That Taking Singulair Leads to Suicide

Kathleen MacNaughton
Kathleen MacNaughton
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Kathleen MacNaughton, RN, is a licensed registered nurse and consumer...

Kathleen MacNaughton

Saturday, September 06, 2008
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In March 2008, in a pre-emptive move, Merck announced that its allergy/asthma drug, Singulair, might cause some people to act on suicidal thoughts. They didn't have any scientific evidence yet, but anecdotal evidence from patients had been coming in. The risk was serious enough that they felt they sh...
  1. Good news, but Where is the media NOW?????
    Anonymous
    Thursday, October 02, 2008 at 10:47 AM

    So where is the news-media now? When this "story" hit it was covered and reported EXTENSIVELY by the media. Every morning show discussed it and pediatricians in particular were swamped with concerned phone calls from parents. Physicians who had been prescribing the product for ten years could not convince parents that based on their experience they felt that the product was safe. Many parents took their children off the medication without consulting their physicians, exposing their child to potential asthma exacerbations by not having them on a controller medication, which was doing the job it was intended to do and one that the child would take daily. Has anyone seen this reported in the media? Has this been covered at all? Where are all those "television" doctors that provide the latest medical news now? The same ones that in March scared all the parents whose children have asthma. What about the print media? Have they covered this development at all or is it buried in the back of the paper where no one will see it? Maybe the drug companies aren't as bad as the media leads us to believe. 

    Reply
    re: Good news, but Where is the media NOW?????
    Kathleen MacNaughton
    Thursday, October 02, 2008 at 11:05 AM

    I have to agree with you, but it's a sad fact that bad news sells -- good news doesn't, or at least not as well.

    Reply
    re: re: Good news, but Where is the media NOW?????
    Anonymous
    Thursday, December 18, 2008 at 05:47 PM

    There's a reason this so called "good news" didn't sell. It proves NOTHING!

     

    Did you know that the study, entitled "Montelukast and emotional well-being as a

    marker for depression: Results from 3 randomized, double-masked clinical trials" involved only 1469 patients, 569 of whom were randomly assigned to montelukast? Follow up data on emotional well being was available for 1352, of whom 536 were assigned to montelukast.

     

    The first trial enrolled 480 patients, of whom 239 were assigned to montelukast for 4 weeks.

     

    The second trial enrolled 500 patients, of whom 165 were assigned to montelukast. Of the 500 patients, 108 were between the ages of 15 and 25 years, and 96 were children ages 6-14 years. Of the 96 children, 32 were assigned to montelukast. The treatment duration was 16 weeks.

     

    The third trial enrolled 489 patients, of whom 164 were assigned to montelukast for 24 weeks; 20% of patients were between the ages of 15 and 25 years.

     

    Do you really think this is sufficient evidence to conclude that there is no link beteween Singulair and suicide? Almost 31 million US prescriptions were written for Singulair in 2007. This drug was tested on approximately 3.5% of this population!

     

    Psychiatric disorders, which are involved in 90% of suicides according to the NLM, are documented post-marketing adverse effects of Singulair. Anxiety and depression were reasons three participants taking montelukast (Singulair) dropped out of the clinical trials. In the medical review for Singulair on the FDA's website, it is documented that a participant taking montelukast developed depression that the researcher considered drug related.

     

    The thousands of posts on medications.com, mostly from parents whose children developed anxiety and depression, experienced suicidal thoughts and actions, suffered seizures, ADHD symptoms, OCD symptoms, vocal and motor tics and a slew of other psychiatic ills while taking Singulair; the FDA AERS reports on patientsville.com; the adverse reaction my son had (which included anxiety, depression, and him wishing he was dead so he wouldn't have to feel so horrible); and the devastating adverse reactions of the children of my friends; lead me to believe, without a doubt, that Singulair is NOT SAFE!

    Reply
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