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Hi Dorothy,   Your local pharmacist might the best one to answer this question, as he/she will be expert in how long the eye drops remain active in the eye and what substances could be safely mixed with them. So, I'd start there.   Speaking from a personal, rather than a professional, viewpoint, I've also found that wrapping ice in a soft washcloth (not a paper towel) and placing it on my itchy, red, swollen allergic eyes provides significant relief when meds aren't doing the job. It might be worth a try. You can also wipe around the eyes gently with the wet washcloth, which is pretty effective at getting rid of any mucus on the eyelashes and outside edges of the eyes. Be sure your son knows to take the ice cloth off the eyes every couple of minutes or so for a minute or two to avoid overexposing the eye tissues to freeze.   Hope this helps, Kathi