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I have been fighting allergies and subsequently depression/anxiety for many years. I have found that when my allergies are really severe and I'm taking a lot of antihistamines that the depression gets exponentially worse. I asked a nurse- practitioner friend of mine and she said YES, most antihistamines when you have to be on them a lot CAN cause depression and when you step down the dosage/frequency of use of them again it can cause anxiety - almost like coming off a lot of caffeine. So I have to choose between feeling better physically/worse mentally, emotionally or vice versa ? Why can't someone find a way to help with the allergies and not blow us all out of the water mentally ?!? Sounds like you've found a doctor who may be able to help you; hope so !