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My daughter has been experiencing these exact symptoms for quite some time, accompanied by weakness in her hands (i.e., it's been harder to pick objects up). She DOES have Juvenile Rheumatoid Arthritis, but it's only in one knee joint; these symptoms are all over. She is only 20 years old and not very active (she doesn't have energy to be more active). The skin sensitivity really grabbed my attention--that has been of longer duration, while the extreme fatigue and hand problems are relatively recent. I would appreciate any additional information.