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I've got the same symptoms, I believe it is a result of an allergic reaction to Zymar, an optical antibiotic.  First I had a severe rash, hives and swelling, and joint pain in my knees and ankles.  The rash faded out over about a week but the joint pain moved to my wrist and shoulders.  I wake up feeling ok, then late afternoon it hits always in my right wrist then sometimes in one or the other or both shoulders.  This has lasted about two weeks, I quit taking the drug as soon as the rash developed.  How long can this last?!
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