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Hi Mar,   Thank you for your question! No, Zyrtec-D does not contain any nonsteroidal inti-inflammatory medications. Zyrtec-D has two active ingredients, cetirizine and psuedoephedrine. Cetirizine is an antihistamine that works to relieve runny, itchy eyes, sneezing, and runny nose. Pseudoephedrine is a decongestant that works to shrink the blood vessels in the nose and relieve symptoms of stuffy nose. You can read more about Zyrtec-D by following this link.   Best of luck with your surgery!! Casey
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