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  Hi Ms. Hall,   Drixoral is a combination antihistamine / decongestant made by Schering-Plough. The antihistamine component is dexbrompheniramine (6mg) which may relieve symptoms of itching, sneezing and nasal drainage. Dexbrompheniramine is a first generation antihistamine which means there is a significant potential to cause drowsiness and fatigue. The decongestant component of Drixoral is of pseudoephedrine (120mg) which is maximum dose (per 12 hours).   I called a local Walgreen's pharmacist and visited a few medical websites in order to find the answer to your question. Drixoral is not available through Walgreens for unexplained reasons according to the pharmacist. One medical site (not Schering Co.) reported that distribution was halted, temporarily, to allow Schering to move the lab responsible for production of the drug to another site. I intend to ask a Schering pharmaceutical rep. about this.   I have spent several minutes trying to find equivalent allergy medications for patients when specific brands are discontinued. Your healthcare provider may be willing to do this for you. Print out the information above (ingredients and doses regarding Drixoral) and ask your doctor about similar brands that may be available. Some people get comparable results from chlorpheniramine or brompheniramine (in comparison to dexbrompheniramine).   Many of these older antihistamines are being outpaced by the newer generation, non-sedating brands (Claritin, Zyrtec and others). Market pressures are causing the disappearance of some of the first generation antihistamines.   Again, get advice from your doctor or pharmacist before trying a different antihistamine medication. The alternative drug may also cause sedation and fatigue. Drug interactions (with other medications you are taking) and other possible adverse effects should also be considered.     Good Luck!   J. Thompson, MD