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Drixoral contained pseudoephedrine, which the DEA decided to regulate, ie make difficult to buy, to decrease illegal methamphetamine production. You have to show a photo ID and sign a log book to get a small quantity. Some drug makers have reformulated to use phenylephrine, less-effective, but unregulated. Drixoral and other regulated OTC sales plummeted from the difficulty involved in buying and essentially non-visible location behind the counter, not to mention all the legal hassles. Unfortunately the nonsedating newer antihistamines do not work as well for many allergy/cold suffers because they are less potent and lack the anticholinergic effect of dexbrompheniramine and brompheneramine which is what dries up the post nasal drip/throat tickle for many. Basically, you can thank the DEA for killing Drixoral, Dimetapp, and many other effective OTC meds as they are interested in fighting their drug war, and could care less about collateral damage to cold/allergy sufferers.