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Monday, November 9, 2009
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Decadron Oral

Drug Interactions


Generic Name: DEXAMETHASONE - ORAL
Pronounced: (dex-uh-METH-uh-sown)

Decadron Oral Interactions

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medications because very serious interactions may occur:

  • live vaccines
  • natalizumab


Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

  • aminoglutethimide
  • aprepitant
  • birth control pills
  • "blood thinners" (e.g., warfarin)
  • bupropion
  • certain cancer drugs (dasatinib, lapatinib, sunitinib, aldesleukin)
  • caspofungin
  • cholestyramine
  • cyclosporine
  • diabetes medications (e.g., glyburide)
  • digoxin
  • drugs affecting liver enzymes that remove dexamethasone from your body (such as azole antifungals including ketoconazole, barbiturates including phenobarbital, macrolide antibiotics including erythromycin, rifamycins including rifampin, certain anti-seizure medications including phenytoin, carbamazepine)
  • drugs that may cause potassium loss (e.g., amphotericin B, "water pills"/diuretics such as hydrochlorothiazide)
  • ephedrine
  • estrogen hormone replacement
  • HIV protease inhibitors (e.g., indinavir)
  • isoniazid
  • mifepristone
  • quinolone antibiotics (e.g., levofloxacin)
  • salicylates (e.g., salsalate)
  • temsirolimus
  • thalidomide


Check all prescription and nonprescription medicine labels carefully since many medications contain pain relievers/fever reducers (NSAIDs such as aspirin, ibuprofen, or naproxen) that may increase the risk of stomach bleeding. Low-dose aspirin should be continued if prescribed by your doctor for specific medical reasons such as heart attack or stroke prevention (usually at dosages of 81-325 milligrams per day). Consult your doctor or pharmacist for more details.

This medication may interfere with certain laboratory tests (including skin tests), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

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