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Thursday, November, 26, 2009
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Alzhemed: Keeping Track of Alzheimer's Treatment Research

David Roeltgen, MD
David Roeltgen, MD
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Neurologist, Professor

A neurologist for over 20 years, Dr. Roeltgen's passions include...

David Roeltgen, MD

Thursday, July 26, 2007
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What's new on the research front for the treatment of Alzheimer's disease? And, what do the terms phase 2 and phase 3 research mean?  In the last two decades, drug studies have become increasingly common. The 1990s was the "Decade of the Brain," and an explosive increase h...
  1. Alzhemed: Keeping Track of Alzheimer\
    semi-recumbent
    Thursday, July 26, 2007 at 04:35 PM

     DR. R  - You have reversed the description of Phase 1 and Phase 2 -

     

    semi

      

    FAQ
    ClinicalTrials.gov - Clinical Trial Phases

    Question: What are clinical trial phases? Answer:

    Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

    • Phase I: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.

    • Phase II: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.

    • Phase III: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.

    • Phase IV: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.
    Reply
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This video animation shows how beta amyloid plaques are created in Alzheimer's patients and how they affect the progress of the disease.

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