Tuesday, May 29, 2012

Does Etanercept (Enbrel) Work on Alzheimer's Patients?

By Bob DeMarco Monday, July 21, 2008

A study reported in the journal BioMed Central BMC Neurology showed that 12 patients improved language recall shortly after treatment with Enbrel, or etanercept, a rheumatoid arthritis drug. The study conducted by Dr. Edward Tobinick, director of the Institute for Neurological Research, was conducted in house without any of the controls usually seen in clinical trials.

The study is limited because people knew they were getting the drug and the result could be explained by the "placebo" effect. It is not unusual for Alzheimer's patients to show improvement in open-label studies.

One has to wonder about Dr. Tobinck's real motives since he charges $10,000-$40,000 per treatment. An outrageous price in my opinion. He does hold several patents on a special method of injecting the drug into the neck.

Hopefully we will see independent studies by scientist without financial interest to determine if this treatment should move forward and if it really works.

It should be noted that this unapproved treatment  is not supported nor endorsed by Amgen. You can read the reaction they posted on the Amgen website.

 

If you want to view a video of the results on patients after the etanercept injection follow this link...Video

 

Other articles on this topic:

Etanercept (Enbrel) in Action, see Alzheimer's patient's memory come alive (Video)


Video Released Of Rapid Alzheimer's Improvement After New Immune-based Treatment

BioMed Central

Reversing Symptoms of Alzheimer's?

Washington University School of Medicine to lead new international Alzheimer's disease research netw
7/22/08 3:26pm

Great info - thanks for posting for our members!  Amazing that this is even considered for real.  But... there is a school of thought out there that follows any research is good research as it keeps people moving in the right direction.  My take - in this case it makes us take pause a bit.  Ensuring that what caregivers and loved ones know about these kinds of studies is so important.  Maybe there is a legit study in the works with this kind of medication.  If there wasn't maybe there will be!

 

For more information on Alzheimer's research, check out the Web Reources page on our site.  It lists links to several of the national organizations focused on this disease and will have additional informaiton on research and studies in the works.

 

All the best, sue

Anonymous
skericheri
8/ 7/08 3:10am

I'm not a fan of Dr. Tobinick's business model...but...as a caregiver for my partner who has Alzheimer's,  I am tired of hearing what Dr. Tobinick's studies lacked.  Reading about people within the Alzheimer Association hoping that independent studies will be done is also getting to be old hat. 

 

With the money that Amgen has spent issuing press releases and sending out glitzy 'I'm sorry but’ letters and informational folders to caregivers and individuals requesting further study of the value of Enbrel as a tool in fighting Alzheimer's, I suspect that a small, double blind, placebo controlled clinical trial in neutral territory could have been funded.  What is the hold up?  Are they naive enough to believe that the requests will stop?

 

Proof of the potential merit of Enbrel treatments is mounting daily.  A clinical trial will eventually have to be done.  Hopefully it will be done sooner rather than later...My loved one is being more compromised every day.  Within the next 12 months I will attempt to seek out of network treatment.  Hopefully my loved one will join the growing pool of ‘anecdotal evidence’.

Ask a Question

Get answers from our experts and community members.

Btn_ask_question_med
View all questions (1484) >
By Bob DeMarco— Last Modified: 10/26/11, First Published: 07/21/08