Ninty percent of retired NFL linesmen have obstructive sleep apnea (OSA). Fifty percent of retired NFL backfield have OSA. MRI-DTI brain scans in subjects who go untreated for their OSA, reveal multiple areas of brain damage. When the area in the brain called area 25 is damaged (in the midfrontal lobes), the result is depression, sometimes suicidal depression. This can be prevented by treating OSA with a CPAP machine. (Recent recommendations are to check blood B3 and B12 levels and treat when too low because they are beginning to look like part of the problem).
Bottom line: EVERYONE should be checked for sleep apnea, low B3 and low B12 and treated when abnormal.