Study says exercise key to preventing Alzheimer’s

  • A recent paper published in the Journal of Biological Chemistry reported on some encouraging results about the benefits of exercise. Researchers at Kyoto University Graduate School of Medicine in Japan concluded exercise is something we can do right now to help prevent Alzheimer’s disease. While the study was done on mice, the researchers feel strongly that people will show similar results.


    A research team led by Ayae Kinoshita compared the effects of diet control, voluntary exercise, and diet control plus exercise in an Alzheimer’s disease mouse model. When the team reviewed the results, they found that “…exercise was more beneficial than diet control in reducing…and restoring memory loss induced by a high-fat diet in these mice. Moreover, Kinoshita's team found that the effect of diet control plus exercise was not significantly different than exercise alone.”

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    Exercise as a route to health is, of course, not news. Last year, in the prestigious science journal Proceedings of the National Academy of Sciences (PNAS), a study was published stating that the premature aging of nearly every organ in the body was completely prevented in mice that ran on a treadmill three times a week for five months.


    Don’t discount diet


    Most of us want to do everything we can do to avoid dementia and other health problems as we age. Wanting is easy. Doing is the problem.


    Take the Mediterranean diet. This diet has been shown in repeated studies to help keep the heart healthy. The heart and brain are now known to require much the same care. With more evidence surfacing that diabetes is clearly linked to Alzheimer’s disease, we need to pay attention.


    Regrettably, my personal resolve to exercise more and eat a healthier diet too often falls short because of my many ingenious “excuses.” Self-discipline fails when I’m tired or my sweet tooth becomes more forceful than the wealth of information I have been exposed to. My guess is that many of you could be in the same boat.


    Most boomers are rightly afraid of developing dementia. Many of us are caring for parents with the disease. With all of this current health research pushing us to do something good for ourselves and our loved ones, one wonders why we don’t “get the memo” to stick with good habits. Perhaps setting too lofty a goal all at once is one of the problems. Therefore, I am going to resolve today to take a more measured approach, starting with baby steps, to finally move forward in the right direction. Exercise. Eat better. Care to join me?



    American Society for Biochemistry and Molecular Biology (2012, June 27) Exercise is key in the fight against Alzheimer's disease. Retrieved from


    McMaster University, CA (2011, February 18) Endurance Exercise Prevents Premature Aging. Retrieved from[status]=3&search[sort]=date+desc&search[has_multimedia]=


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Published On: June 28, 2012