Wednesday, February 15, 2012

Monday, September 14, 2009 dfowler1976 asks

Q: Complex case of having schizophrenia now worried about EOAD

Here goes, this is a complex one I think.  I started becoming symptomatic in 01 thinking my neighbors were out to harm me and that I could read their thoughts.

 

Then in 02 I had terrible panic attacks along with voices saying the gov was beaming electromagnetic weapons at me.  I started to believe it because it didnt' feel like a normal panic attack at all.

 

From 02 to lat 04 I did ok, but still heard voices.  I noticed that my cognition was not as good for remembering stuff I read, and I was 27, 28 at the time.  But thinking back even in college I struggled with memory and certain problem solving tasks.  So at age 28 I think my cognition was still about the same.

 

Then unexpectadly in early of Jan 05 I became paraonid that a group of peers from my high school were out to kill me.  I was living in a private group home at the time and the director checked me into a mental hospital.  To make a very long story short I heard non-stop voices of a persecution kind saying I was being tortured or that I would die.  I also noticed a severe drop in overall cognition around this time.  I was in a severe mental fog and could barely read or even think.  I noticed the thoughts in my head seemed far softer over just a week.

 

So I stabalized on meds and was moved into a public group home where I had no energy, had high anxiety, and felt like total garbage just smoking and lying in bed barely able to comprehend the television.

 

This lasted for over 2 years!  And finally in early 08 I got my own apartment and gradually over time I became more cognitively with it and could read a bit again, but still forgot the vast majority of what I read.

 

I continued to make progress, went to a psychologist, psychiatrist and two neurologists and had two MRI's which both came out normal.

 

So now over just the last 4 plus months I've noticed a decline in my memory.  I'm 33 now and alzheimer's or other dementia's don't run in my family.  But I will forget things like cars I've owned, only to recall the info later.  I forget famous celebrities that I used to know well, and I forget things that I would normally have known.

 

I have poverty of thought, presumably from the schizophrenia, and I theorize that may or may not have something to do with it.

 

I'm on antipsychotics and antidepressions, can still write fairly well, but make spelling mistakes more than I used to, but I was always not a great speller.

 

I passed the mini mental state exam several times and did average on a neuropsyche test, with my math being substantially poorer than when in high school and college.

 

My verbal IQ was 117 and overall was 103.  I was far smarter prior to the schizophrenia.

 

So my question boils down to, is this cognitive decline due to the schiz?  Or is there two things going on here?  Is this a precursor to some kind of dementia like EOAD?  Of am I in a mild stage of it already? 

 

I don't have any confusion, can drive just fine, and can plan ahead, all tasks that many people with schizophrenia often have trouble with.

 

So that's me in a nutshell.  Again, I had cognitive impairment from an acute psychotic episode, and I've improved, now I'm noticing substantial lapses in my memory, and continue to have poverty of thought and other negative sz symptoms.

 

Thank you for your time.

 

Devon

 

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Answers (1)
9/14/09 8:44am

Hi Devon,

This is indeed complicated. I know just enough about mental illness (I'm not a medical person, but have relatives with similar issues) to know that the psychiatric drugs needed for major depression, OCD, anxiety, schizophrenia and other mental issues can cause confusion and memory problems.

 

I'm not saying you don't have early on-set AD, but your tests seem good. I don't know if there is any way for doctors to tell you more than they have. Have you mentioned this possibility to the neurologist? Have you seen anyone with experience with AD? It's possible one of the drugs for AD that help with blood flow to the brain may help, but you will be adding more side effects to those your already have, so that move would need careful monitoring.

 

Drugs are wonderful and necessary, as you have seen, but they all have side effects. You might want to talk with a pharmacist as well as doctors. Pharmacists know drugs and their side effects better than many doctors. 

 

I'd be aware of AD, but since you've had all of these other issues, that may not be the case. Just stay on top of it, bring it up to your doctors, and keep up the good work. You have been through a great deal and will always have to balance side effects with the help the drugs give you. It's a hard road, but it's better than not getting help.

Take care,

Carol

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9/14/09 2:34pm

Well I've read up enough on schizophrenia, various studies, articles and talked to psychiatrists who specialize in this field to know that one of the core features of schizophrenia is having substantial to severe cognition problems including memory, spatial reasoning, abstract thinking including problem solving, and since it's been said that almost all of the brain of schizophrenic subjects is involved often schizophrenic cognitive impariment can mimic that of Alzheimer's, and some severely cognitively impaired patients with schizophrenia actually do worse on certain memory test than patients with Alzheimer's.

 

Again, My cognitive problems happened very drastically, and over the period of a week in Jan of 05, due to a psychotic episode, so it was NOT the meds.  Since then my cognition has improved a lot, but I also know that according to studies cognitive impairment in schizophrenia usually stays about the same over the years with slight fluctuations.

 

Getting back to my severe cognitive decline in early 05/ late 04, from that point on I had, and still have, trouble remembering what I did that day, which I know can be a symptom of Alzheimer's.  The problem is with me this happened over a period of a few days to a week, which is not consistant with an Alzheimer's progression, as it moves usually slowly.

 

The main thing I'm concerned about is my APPARENT recent problems with memory such as famous celebs, facts and figures, and people I know, but not people I know really well.  Only one time did I forget the name of my pdoc for about half an hour, then remembered.  So I'm concerned that my memory MAY have gotten worse, however I also am much more acutely aware of any cognitive changes in the last year or so, as I was in too much of a daze horrific state for a few years after this acute episode.  So it is complex and I will address things with my neuro today.

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9/14/09 3:09pm

Something like a mini-stroke could cause sudden problems. It's excellent that you are seeing your doctor today. You'll have to keep working on this until you come to some diagnosis or reason why this happened. Good luck with it all.

Carol

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9/14/09 7:48pm

I saw my neurologist, and he is one of the most highly recommended in the state of Ma. from sources at Mass General Hospital's Schizophrenia clinic, (also nationaly reknown for their work in cognitive dysfunction in schizophrenia.)

 

And he basically reassured me that my symptoms were in keeping with a schizophrenia diagonsis.  He is a firm believer in Emil Kraephlin's hypothesis that cognitive impairment in this disease is a form of dementia.  At the time Emil thought it was usually progressive, but the newer antipsychotics have proven eficacious in slowing down, halting, and even reversing cognitive impariment that is found in short, long, working memory and other executive functions.

 

My neuro assured me that it is rare for schizophrenia to turn into AD unless it's of a late onset or very late, in which case 1/3 of patients progress into Alzheimer's and other dementias.  This maybe because very late onset sz maybe Alzheimer's in disguise or the two could exist together.

 

Most cognitively impaired schizophrenics remain stable, at least into old age, and many in their older years.  He thinks my recent memory lapses maybe something else or just a fluke, but he told me to moniter myself and see him regularly to see if there are any more changes.

 

So, although I'm fairly sure it's not EOAD I'm not going to completely dismiss it, and I will keep my eye out for futher changes.  I'm trying to be as rational and realistic as possible.

 

Devon

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9/15/09 7:14am

Wonderful new, Devon. It makes complete sense.

You are a strong person and to be commended for your approach to your disease and steadiness in addressing issues.

Take care,

Carol

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9/15/09 11:50am

Thank you Carol, this has been a bit more than scary, and when I don't get enough sleep it gets even worse, I'm currently in an instant messenger support group for others suffering from various dementia related symptoms.  I wish us all the best of course.  I've become good friends with these people, all from Great Britain.  Your truthfulness with me proved instrumental in my long working out of my diagnosis.Wink

 

I have nothing but empathy for all dementia sufferer, and wish there was better funding for diseases like AD.

 

Sincerely,

Devon

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9/15/09 1:04pm

I, too, wish you and all of your friends the best. I'm so glad you have found support. It helps a lot when we don't feel so alone.

Best,

Carol 

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9/15/09 4:52pm

Thank you Carol, and if you're going through anything, I wish you the best too.  Again we need to raise awareness and get better funding for Alzheimer's from the gov to individual or group fundraising.

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