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Unlike normal age related memory loss people with Alzheimer's find themselves unable to carry out the ordinary events of daily functioning and become unable to live independently. However in the early stage of Alzheimer’s memory impairments and other early symptoms and memory changes of aging can be difficult to differentiate.
Scientists from the Universityof Illinois have developed a cognitive task that helps identify the differences and can help dictate treatment approaches and exclude other illnesses. As we know the hippocampus, a part of the brain, is important in binding together information of an event where information is stored in different parts of the brain. It is also part of the brain that is affected by Alzheimer’s disease. So if someone remembers a person called, for example, Julie, they can then also remember what she looks like by composing a relational memory.
The test that these scientists put together looks at a task that tests participants...
A new study has concluded that a type of age-related memory loss not related to Alzheimer’s disease could be reversible. A team of Columbia University Medical Center (CUMC) researchers, led by Nobel laureate Eric R. Kandel, MD, has concluded that deficiency in the hippocampus of the protein RbAp48 is likely a significant contributor to age-related memory loss. The great news is that this form of memory loss can be reversed.
For the study, Kandel’s team used postmortem human brain cells as well as mice. The conclusion of the study offers the strongest causal evidence to date that age-related memory loss and Alzheimer's disease are distinct conditions. The findings were published in the August 29, 2013 online edition of Science Translational Medicine .
The study focus was to look for direct evidence that age-related memory loss is a separate disease from Alzheimer’s disease. The researchers performed gene expression analyses of postmortem brain cells from ...
This is the first randomized controlled trial comparing two different treatment approaches for patellar (kneecap) dislocation. Forty patients with dislocation of the kneecap were included. All patients had a traumatic injury either from a military exercise or a sports activity. All of the patients were in the military. Most were men between the ages of 19 and 22. The real question behind this study was: should a primary (first-time) patellar dislocation be treated right away with surgery? Or can it be managed nonoperatively with a knee orthosis (brace). What are the long-term results of both approaches? There are many surgical ways to stabilize a dislocated patella. In this study, two types of procedures were used based on the type of damage present. Besides a dislocated patella, patients also had an injury to the patellofemoral ligament requiring repair or reconstruction. The mechanism of dislocation was a sudden displacement of the patella laterally (away from the other knee). The sof...
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