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THE AFA social service executive answered a similar question some time ago:
http://www.healthcentral.com/alzheimers/c/question/56623/29186
Hope his answer helps.
I heard that changing homes does affect the patient. However if you need to do what you need to do, then it may be worth a shot. The key is your sister can be closer. Maybe she can ask the administrator of the new home to assist her by talking to him and etc.
Good luck,Nina