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Hi, Caring KB,   You are right to be concerned. First of all, I'd suggest that you have someone assess your uncle's driving ability. I didn't have to do this with my mom, but did watch the documentary on HBO's Alzheimer's Project that showed a clip of someone with Alzheimer's driving, which was unnerving and showed a very unsafe driver. The woman who was driving claimed to be able to drive perfectly, but didn't understand how to back up the car, what common street signs meant, or how to follow directions. Even after the driving test, she claimed to be a sound driver and was upset by the news. Based on this segment, there is a possibility that your uncle is overestimating his ability to drive.   If they want to take the trip (which sounds like great fun), I'd strongly suggest that if your aunt and uncle opt to fly and possibly limit driving by taking tours, having outings with old friends, etc. Perhaps your aunt can suggest this way of getting to and around Alaska by suggesting that they will have more time and energy for sightseeing and visiting. Additionally, the time they spend there will be less stressful by not driving.   Take care and keep us posted!   Dorian