Depression
Depression is one of the most common psychiatric disorders.
Symptoms of depression are often subtle and unrecognized both by
patients and physicians.
The brain contains a network of interconnected nerve cells
called neurons. The junction between the neurons is called the
synaptic junction.
The transmission of impulses from one neuron to another is
facilitated by chemicals called neuro-transmitters.
The impulse triggers the release of neurotransmitters from one
neuron, which cross the synaptic junction and attach themselves to
the receptors in the adjacent neuron sending the message
through.
Later the neurotransmitter returns to the initial neuron via the
reuptake channel.
One of the causes of depression is believed to be the depletion
of the amine neurotransmitters, serotonin and norepinephrine.
The anti depressant drugs increase the availability of
neurotransmitters at the synaptic junction by blocking the reuptake
channel.