Cymbalta

Other medications, including over the counter medications can impact the effectiveness of Cymbalta. Before using any of the following, consult your physician:

• Cold or allergy medications
• Narcotic pain medication
• Pain/arthritis medication
• Sleeping aids
• Muscle relaxers
• Seizure medications

Certain medications should be avoided when taking Cymbalta. These include:

• Fluvoxamine
• Sibutramine
• Thioridazine
• Trytophan

Although the medications listed here can cause interactions and should not be taken with Cymbalta, it is important to discuss all medications you may be taking with your doctor to avoid any serious interactions.

Side Effects

There are a number of common side effects with the use of Cymbalta. Many of these should lessen or disappear after a few weeks of taking the medication. If they do not disappear or worsen, you should contact your doctor:

• Stomach problems, such as nausea, constipation, or loss of appetite
• Fatigue, drowsiness or dizziness
• Dry mouth
• Increased sweating
• Blurred vision
• Increased yawning

Although many people take this medication without experiencing serious side effects, you should be aware of conditions that would require you to contact your doctor immediately:

• Changes in mood (suicidal thoughts, high energy/nervousness)
• Fainting
• Tremors or shaking
• Sexual side effects (decreased interest or inability to perform sexually)
• Difficulty urinating or changes in the amount of urine produced
• Weight loss

There are also more serious side effects that are rare, but may occur and would require you to contact your doctor right away:

• Stomach pain or vomiting that looks like coffee grounds
• Stools that are bloody, black or tarry or dark urine
• Bruising or bleeding more easily
• Muscle weakness
• Yellowing of eyes or skin
• Seizures
• Extreme tiredness
• Heart palpitations or pounding heartbeat

There is also a condition referred to as serotonin syndrome that may occur when Cymbalta is combined with certain medications, such as prescription medications for migraine headaches, other antidepressants or medication for obesity. Symptoms of serotonin syndrome can include hallucinations, restlessness, problems with coordination, rapid heartbeat, extreme dizziness, fever of unknown origin, severe stomach problems and twitching of muscles. If you are experiencing any of these symptoms, you should seek immediate medical help.

Allergic reactions to Cymbalta can also sometimes occur. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, and problems breathing. You should call 911 or seek immediate medical help if you are experiencing an allergic reaction.

Pregnancy and Nursing

Cymbalta may cause harm to an unborn baby, especially if taken during the third trimester of pregnancy. Talk with your doctor if you are pregnant or plan to become pregnant while taking Cymbalta.