- Allergic reaction, including hives, itching or trouble breathing
- Chest pain, tightness in the chest, palpitations or irregular heartbeat
- Sudden or severe mood changes or bizarre behavior
- Fever, chills, swelling of the throat or mouth
- Memory problems
- Increased anxiety including panic attacks
- Tinnitis (ringing in the ears)
- Seizures, tremors or confusion
- Shortness of breath or difficulty breathing
- Bruising or bleeding easily
- Vision problems
In addition, some people have experienced increased thoughts of suicide or a deepening of depression when taking this medication. If you are having thoughts of suicide or your depression/anxiety increase, contact your doctor immediately or seek emergency medical care.
Serotonin syndrome may also occur. This is possibly fatal and may happen if you take Effexor while taking MAOIs or triptan antidepressanst. Symptoms of serotonin syndrome can include agitation, confusion, hallucinations, coma, rapid heartbeat, nausea, vomiting or diarrhea. Contact your doctor immediately if you are experiencing these symptoms.
Drug Interactions
Some medications may interfere with the effectiveness of Effexor, or Effexor may interfere with the effectiveness of other medications. It is important to discuss all medications you are currently taking with your doctor. This includes supplements, over-the-counter medications and vitamins.
In particular, you want to make your doctor aware of the following medications:
- Diet medications
- MAOIs
- Antidepressants
- St. John's wort
- Anticoagulants (including aspirin and ibuprofen)
- Diuretics
- Antifungal medication
- Antipsychotic medications
Pregnancy and Nursing
Effexor may cause harm to an unborn child, especially if used during the last trimester of pregnancy. If you are pregnant, or plan to become pregnant, talk with your doctor about the possible benefits of taking Effexor and the risk to your unborn child. You and your doctor can determine if the benefits outweigh the risks involved.
Effexor can also be passed to a child through breast milk. You should not take Effexor when breast-feeding.
Sources:
"Effexor", 2009, March 4, Author Unknown, Drugs.com
"Effexor Oral", 2007, Author Unknown, First DataBank, Inc., Health Central
"Effexor", 2009, Author Unknown, RxList

