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Sunday, May 17, 2009 ebonyrae, Community Member, asks

Q: zyprexa withdrawal

What is the best way to get off zyprexa? I have been taking 1.25mg nightly for 2 years. Every time I try to get off them I have panic attacks???

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Answers (3)
Eileen Bailey, Health Guide
5/18/09 8:37pm

Thank you for your question and welcome to


Although Zyprexa is not considered addictive, it is not recommended to suddenly stop taking this medication as you may need time to adjust to not having the medication. Many physicians will suggest weaning off the medication over a period of time to reduce the withdrawal symptoms associated with stopping this medication.


It is important to talk with your doctor about stopping this medication. The panic attacks you are feeling may be a symptom of Zyprexa withdrawal or could be a symptom of anxiety and the Zyprexa is helping to reduce those symptoms. It would be impossible to say based on what you have asked in your question.


The best advice would be for you to discuss stopping Zyprexa with your doctor. He or she would be best able to determine if you should wean off the medication and whether what you are experiencing is a symptom of withdrawal.



ff, Community Member
10/31/11 7:35am

how do you get 1.25mg zyprexa?


Copy_cat, Community Member
3/26/12 1:06pm

Please do a google search for zyprexa withdrawal horror stories, alot of info there

Copy_cat, Community Member
3/26/12 1:16pm

I had to start taking ativan to get off it. I had all the vommitting, panic attacks and couldent eat.


I then had to get off ativan...



If you goto the hospital try and print this collection of stories and bring it.



Often they will blame the withdrawal effects of zyprexa on "your Illness" and say "Its in your head" leading to a Psych lock up and more psych drugging instead of medical help.


This is what happends to many Zyprexa victims,  MEDICAL HELP demand it. has good information also to help you get MEDICAL treatment.


You have the right to decide to terminate any given treatment.


Since the mental health system got you started on medications, it also has a responsibility to help you terminate that treatment as safely as possible if that is your choice.

sungirl, Community Member
6/23/12 11:45am

I don't think that's a good stie to go to if someone needs help.  That site will only scare the person more and offers no real solution, just a bunch of people telling about their stories.  There are too many sites like that, we need to know more about solving the problem.  Such as, are there vitamins, or any supplements that one can take while withdrawing.., etc.

Donna-1, Community Member
3/27/12 6:14am

For many years (beginning in 1997) I took 40mg of Zyrpexa every day.  Talk about zombieland!  The Walking Dead!  Gradually (till about 2008) this was reduced to 15mg by the doc, and on my own I reduced it down to about 3mg by just cutting the 15mg pills up.  I was still a zombie at 3mg.  But no matter how many years I ended up being on it (13) it seemed like I could never get off of it completely without severe vomiting, relapsing into depression and schizophrenia, and often ending up back in the hospital.  Once I started such severe vomiting I called 911 because I was afraid I was going to die!


So others of you out there might think, "Then why get off of it if it is helping?"  Because the symptoms are horrific for many people.


Are you using this medication for anxiety?  If so, it looks like your doctor could help you switch to a different anxiolytic like Buspar, which is non-addictive.  If you are taking Zyprexa for schizophrenia, you might ask your doctor to switch you to one of the other atypicals like Latuda, which just came out last year and the side effects aren't as bad (or at least I find them more tolerable.)  When my doctor switches me mid-stream from Zyprexa to any other antipsychotic, he doesn't even taper one off and one on.  He just switches, and I've never had Zyprexa withdrawal when that happens.


Just a few ideas to discuss with your doctor.  My heart goes out to you.  Zyprexa can be both life-saving and nasty stuff.

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By ebonyrae, Community Member— Last Modified: 03/30/13, First Published: 05/17/09