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Monday, January 19, 2009 dewalt.17, Community Member, asks

Q: I take cymbalta, when I miss a dose

When i some times miss one dose of cymbalta I get brief waves of tingling and numbing sensations that come and go.. Is that typical ?? or should I dicuss it w/ my dr.?? 



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Answers (3)
Dr. Diana L Walcutt, Health Guide
1/19/09 6:36pm

Hi Dewalt: Always talk with your doctor about any concerns you may have. Typically, missing a dose here and there shouldn't be a problem, unless you've only been on the med for a short period of time. However, reactions differ between patients. So, call your doctor's office and see what they say,

Hope this helps,

Dr. Diana Walcutt

Mary, Community Member
10/27/09 5:55pm

My cymbalta ran out after a Thursday morning dose. I forgot to pick up the RX on Friday and my pharmacy is closed on Saturday and Sunday. On Monday morning, I was shakey with balance issues. I also was experiencing visual disturbances. I got to work, but was unable to function. It felt as if I was having a full blown anxiety attack. I did pick up my RX and took a dose immediatly. That day was shot. The next day my shakiness decreased, but I had terrible cold sweats. Is this typical when missing 3 days? The drug has been helping. I anticipate being on it or other forms of antidepressent for the remainder of my life. I lapse back into severe depression whenever I stop meds. I have been hospitalized twice. I would really like to learn more. I see my psychiatrist next week.

1/19/09 8:42pm

dewalt - As a general rule always discuss matters of concern with your physician. The effects of discontinuing treatment are influenced by the dose taken and the length of time you have been on it, among other factors. Research data suggests that in 2% or more of the patients studied, abrupt discontinuation of treatment resulted in symptoms like dizziness; nausea; headache; paresthesia; vomiting; irritability; and nightmare. Although it seems unlikely that missing only one dose would cause problems, it is not impossible. Again, speak to your physician in order to be sure that there is nothing to worry about.


Rick Wirtz


Rick Wirtz is a Psychologist, not a psychiatrist or medical doctor. Although the majority of Psychologists are not authorized to prescribe medications or give you specific advice about them, they typically have experience working with patients who take a variety of medications. The response above is not intended to diagnose or treat any medical or mental disorder. Any information given in a post about medication is for educational purposes only and primarily to aid you in having an informed discussion with your own physician



NoTW, Community Member
2/10/09 3:18pm

I used to be fine if I missed a dose of Cymbalta, but in the past couple months, I find that I get the same thing, and I get dizzy and light-headed. Sometimes I feel a little nautious, too, but once I take my meds I am fine. It's not fun, but I think it's just one of the things you have to deal with if on this medication. Undecided

RCR, Community Member
5/29/13 10:41am

I occasionly forget a dose and every time I do I get side effects ranging from  a "zinging" in my head to dizziness and  nausea. I started taking Cymbalta several years ago for peripheral neuropathy. I would like to stop now as I think the effect od missing a dose are getting worse.

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We hope you find this general health information helpful. Please note however, that this Q&A is meant to support not replace the professional medical advice you receive from your doctor. No information in the Answers above is intended to diagnose or treat any condition. The views expressed in the Answers above belong to the individuals who posted them and do not necessarily reflect the views of Remedy Health Media. Remedy Health Media does not review or edit content posted by our community members, but reserves the right to remove any material it deems inappropriate.

By dewalt.17, Community Member— Last Modified: 07/29/13, First Published: 01/19/09