Last week the U.S. Food and Drug Administration approved the first generic versions of Cymbalta (duloxetine delayed-release capsules), a prescription medicine used to treat fibromyalgia, chronic musculoskeletal pain, diabetic neuropathy, depression and generalized anxiety disorder.
Aurobindo Pharma Ltd., Dr. Reddy’s Laboratories Ltd., Lupin Ltd., Sun Pharma Global FZE, Teva Pharmaceuticals USA, and Torrent Pharmaceuticals Ltd. Have all received FDA approval to market duloxetine in various strengths.
“Health care professionals and consumers can be assured that these FDA-approved generic drugs have met our rigorous standards,” said Kathleen Uhl, M.D., acting director of the Office of Generic Drugs in the FDA’s Center for Drug Evaluation and Research. “Generic drugs offer greater access to health care for many people.”
Are Generic Drugs Really the Same?
In the news release announcing the approval of generic versions of Cymb...
Generic name: Duloxetine
Cymbalta is an antidepressant medication. It has been approved for use in treating symptoms of depression and generalized anxiety disorder (GAD). It is also used to treat fibromyalgia and diabetic neuropathy. Cymbalta is a selective serotonin and norepinephrine reuptake inhibitor (SSNRI). Serotonin is a neurotransmitter in the brain and depression has been linked to the inability to create enough serotonin. Norepinephrine is another neurotransmitter linked to depression. Cymbalta targets both serotonin and norepinephrine, unlike SSRIs, which only target serotonin. Both of these neurotransmitters can impact mood. The medication works to block the neurotransmitters from reentering the nerves, allowing more of the neurotransmitters to remain active.
Clinical trials have shown Cymbalta to improve mood, increase appetite and allow for better sleep. It can also increase energy and decrease nervousness.
Generally, this medication is started...
You've probably seen the television commercials or magazine ads for Cymbalta, and you might be wondering what makes it different from other antidepressants. Since I know that the writing in the medication insert is dense enough to make your eyes cross and your head nod, I've distilled some of the basic information about it here.
Cymbalta (duloxetine) is a serotonin-norepinephrine reuptake inhibitor (SNRI) prescribed for the treatment of depression, anxiety, stress urinary incontinence, nerve pain and fibromyalgia. Other antidepressants in the SNRI family that you may have heard of are Effexor and Serzone. SNRIs act on two neurotransmitters in the brain, namely serotonin and norepinephrine, to prevent their reabsorption after they act on receptors.
As with several other SNRIs, Cymbalta's most common side effects are nausea, dry mouth, drowsiness, headache, changes in appetite, vivid dreams, dizziness and sexual side effects. This is ...
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