Hi Ellie: I'm sorry I didn't see your question sooner! Desyrel, or Trazodone, is an antidepressant with the typical side effect profile of most antidepressants. One of them listed is gastrointestinal problems such as nausea, vomiting, loss of appetite, diarrhea or constipation. You may need to speak with your doctor to see if you are taking too high a dose, or need to switch to something else.   Best of luck, Dr. Diana Walcutt   *Dr. Walcutt is a Psychologist. Dr. Walcutt's answers are not intended to diagnose or treat any medical or mental disorder. Any information given in a post about medication is for educational purposes only, and primarily to aid you in having an informed discussion with your own Psychiatrist/Physician.