FROM OUR EXPERTS
Generic name: Duloxetine
Cymbalta is an antidepressant medication. It has been approved for use in treating symptoms of depression and generalized anxiety disorder (GAD). It is also used to treat fibromyalgia and diabetic neuropathy. Cymbalta is a selective serotonin and norepinephrine reuptake inhibitor (SSNRI). Serotonin is a neurotransmitter in the brain and depression has been linked to the inability to create enough serotonin. Norepinephrine is another neurotransmitter linked to depression. Cymbalta targets both serotonin and norepinephrine, unlike SSRIs, which only target serotonin. Both of these neurotransmitters can impact mood. The medication works to block the neurotransmitters from reentering the nerves, allowing more of the neurotransmitters to remain active.
Clinical trials have shown Cymbalta to improve mood, increase appetite and allow for better sleep. It can also increase energy and decrease nervousness.
Generally, this medication is started...
I take Cymbalta for fibromyalgia and I still get severe migraines. My doctor prescribed Imitrex. In the past before I started taking Cymbalta, my dose was 100mg. now that I take Cymbalta I have been afraid to take Imitrex even if I get a migraine. I did talk to the pharmacist and she said I could take half of my 100mg Imitrex. My question is if I take Cymbalta in the morning and get a migraine say 8 to 10 hours later is it alright to take half like the pharmacist said or exactly how many hours after taking Cymbalta would it be safe to take half of the Imitrex? Kim.
Taking triptans such as Imitrex and antidepressants such as Cymbalta presents a risk of serotonin syndrome. Taking the two types of medication together is not contraindicated, but there's a warning for patients to know the symptoms so they can report the symptoms to their doctors if they occur. For more perspective on ...
Lisa Nelson RD #8: Please clear up the confusion about grapefruit and medication! Is it safe for individuals taking medication for heart disease, such as Lipitor, to eat grapefruit or drink grapefruit juice? When is grapefruit not allowed?
Dr. Shelby-Lane: I am including information that may help answer your question about grapefruit and a variety of nutritionals that affect statin drugs for the lowering of cholesterol.
Zocor (Simvastatin), for example, is a Statin drug, used to lower high cholesterol levels, and also known as HMG-CoA reductase inhibitor. Zocor may affect the absorption or utilization of vitamins E and coenzyme Q10. Tests showed the average concentration of coenzyme Q10 in blood plasma decreased by approximately 50% after statins were used for 30 days. Supplementation is considered beneficial.
Grapefruit and grapefruit juice may increase the effects of HMG-CoA reductase inhibitors and should not be consumed at the same time. It i...
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