Generic name: Duloxetine
Cymbalta is an antidepressant medication. It has been approved for use in treating symptoms of depression and generalized anxiety disorder (GAD). It is also used to treat fibromyalgia and diabetic neuropathy. Cymbalta is a selective serotonin and norepinephrine reuptake inhibitor (SSNRI). Serotonin is a neurotransmitter in the brain and depression has been linked to the inability to create enough serotonin. Norepinephrine is another neurotransmitter linked to depression. Cymbalta targets both serotonin and norepinephrine, unlike SSRIs, which only target serotonin. Both of these neurotransmitters can impact mood. The medication works to block the neurotransmitters from reentering the nerves, allowing more of the neurotransmitters to remain active.
Clinical trials have shown Cymbalta to improve mood, increase appetite and allow for better sleep. It can also increase energy and decrease nervousness.
Generally, this medication is started...
Generic Name: DULOXETINE - ORAL Pronounced: (doo-LOX-e-teen) Cymbalta Oral Interactions
Drug interactions may change how your medications work or
increase your risk for serious side effects. This document does not contain all
possible drug interactions. Keep a list of all the products you use (including
prescription/nonprescription drugs and herbal products) and share it with your
doctor and pharmacist. Do not start, stop, or change the dosage of any
medicines without your doctor's approval.
Some products that may interact with this drug
other drugs that can cause bleeding/bruising (including
antiplatelet drugs such as clopidogrel, NSAIDs such as ibuprofen, "blood
thinners" such as warfarin)
Other medications can affect the removal of duloxetine
from your body, which may affect how duloxetine works. Examples include
cimetidine, quinolone antibiotics (such as ciprofloxacin, enoxacin), among
In the summer of 2005, I met several MS patients who were undergoing Solumedrol treatments. I was in the infusion clinic for a release as were several other patients. One patient (I’ll call her Mary), however, was there for a different reason. She had just had a baby.
Before the baby was born, Mary had a plan. She had gone off of her disease-modifying drug (Rebif) when she learned she was pregnant and she planned to breastfeed for a certain period of time before going back on Rebif. The Solumedrol treatment was to ward off any postpartum MS rebounds.
The decision to breastfeed was an important one to Mary as she felt that it was vital to the well-being of her new daughter. But how did Mary decide what drugs to take or not take during that time period?
This week is World Breastfeeding Week and thanks to the LactMed database, offered by the National Library of Medicine, we can research the effect of different drugs and chemicals on lactation.
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