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Absolutely! Cigarette smoke is a notorious asthma trigger.
Dr. James Thompson on this site wrote an in-depth piece about tobacco smoke (either from cigarettes or from "hookahs") and its affects on the lungs, particularly the lungs of asthmatics. I'd give it a read.
In general, asthmatics should steer clear of cigarette smoke -- they should not smoke and they should avoid second-hand smoke.
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