What is the concern about Singulair (montelukast)? Singulair is a major drug in asthma treatment – it is important to review recent developments and put these findings in perspective of overall asthma care for individual patients. Singulair (montelukast) Singulair (manufactured and marketed by Merck and Co.) is a drug of the so-called anti-leukotriene class that is used for control of symptoms of asthma and allergic rhinitis (hay fever) . It was initially approved by the U.S. Food and Drug Administration (FDA) for use in asthma in 1998 (its indication was broadened to include treatment of allergic rhinitis in 2003). In the two broad classes of asthma medications -- quick-relief (typically bronchodilators, such as Xopenex or Foradil ) and long-term controllers (typically anti-inflammatory medications such as Azmacort or Medrol ) -- Singulair falls in the latter class. The anti-leukotrienes block the action of several molecules that not only cause inflammation in the breathing tub...
In March 2008, in a pre-emptive move, Merck announced that its allergy/asthma drug, Singulair, might cause some people to act on suicidal thoughts. They didn't have any scientific evidence yet, but anecdotal evidence from patients had been coming in. The risk was serious enough that they felt they should let the public know. However, the FDA decided not to take it off the market or even issue a black box warning until the issue could be studied more closely.
Over the past few months, that's exactly what the American Lung Association has endeavored to do. Their findings are due to be published in an upcoming issue of the Journal of Allergy and Clinical Immunology .
So, two researchers at the Lung Association did what they call a "look back" study , where they analyzed data from Singulair's original pre-release clinical trials. They searched the data for clues that Singulair was having an effect on a patient's emotional well-being. The good news is they found no such signals...
Over-the-counter birth control methods are used during sex to avoid pregnancy and sometimes to prevent sexually transmitted infections (STIs). Over-the-counter means that they can be purchased by anyone, without a doctor's prescription.
For more information about birth control options, see:
Birth control and family planning
Birth control - over the counter; Contraceptives - over the counter
Over-the-counter birth control methods are not as effective against pregnancy as some prescription methods. However, they are more effective against STIs than any other method except not having intercourse (abstinence). They enable people to protect themselves against pregnancies and STIs without having to:
Deal with long-term side effects
Spend a lot of money
Wait for a doctor's appointment
A male condom is a thin sheath pla...
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