What is the concern about Singulair (montelukast)? Singulair is a major drug in asthma treatment – it is important to review recent developments and put these findings in perspective of overall asthma care for individual patients. Singulair (montelukast) Singulair (manufactured and marketed by Merck and Co.) is a drug of the so-called anti-leukotriene class that is used for control of symptoms of asthma and allergic rhinitis (hay fever) . It was initially approved by the U.S. Food and Drug Administration (FDA) for use in asthma in 1998 (its indication was broadened to include treatment of allergic rhinitis in 2003). In the two broad classes of asthma medications -- quick-relief (typically bronchodilators, such as Xopenex or Foradil ) and long-term controllers (typically anti-inflammatory medications such as Azmacort or Medrol ) -- Singulair falls in the latter class. The anti-leukotrienes block the action of several molecules that not only cause inflammation in the breathing tub...
Millions of Americans in pursuit of a remedy for stuffy nose and sinus pressure turn to over the counter (OTC) nasal sprays because of their quick action, availability and presumed safety. But did you know prolonged use of topical nasal decongestants (TNDs) often leads to addiction? Case in Point: A 32-year-old male was referred to me because of complaints of chronic nasal blockage. The patient suspected his problem was hay fever (allergic rhinitis). During the interview, he revealed that a year ago he began to have trouble sleeping because of a stuffy nose. He felt considerably better after using a TND before going to bed. Within 2 weeks he began to awaken in the middle of the night requiring another dose of his nasal spray for relief. One month later he required doses 4 times daily in order to avoid severe nasal congestion. By the time I saw him, he was going through almost a bottle of nasal spray daily. His diagnosis was Rhinitis Medicamentosa (RM) which means nasal inflammation (rhi...
Medications to have at home
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