So far so good. Holiday heavy-duty blahs haven't hit yours truly.
How about you? One sure-fire way to continue one's toxic-veiled existence, blunting sheer-joy potential for yet another year, is smoking cigarettes. By that I mean this: chronic nicotine use contributes to one's blahs. Mandatory smoking - via one's deeply entrenched habit - isn't fun, isn't fulfilling; 'tis draining. I remember over 15 years ago when smoking was a must for me, a matter of course, associated with everything else, superseding everything else, yet not noticed, per se, just taken as a given.
Experienced with perhaps an internal - and, at times, external - sigh of resignation, a faint phlegm-coated realization that I was hooked, but "I can't do anything about that right now." Is this you? Are you smoking as you read this blog post?
Try this. Stand up, take your cigarette with you to the most convenient mirror in your home. Look directly into your mirror and take a deep drag. Continue staring at yourse...
In this entry, I would like to discuss the implications of some recently published basic science research on the function of beta agonists -- the most common class of quick-relief inhalers that includes albuterol. While the research was done with mice, it has implications on human asthma treatment, particularly in light of recent controversies of the risks of long acting beta agonists (LABAs) in asthma treatment.
How beta agonists work and what do mice have to do with this? Beta agonists get their name from their mechanism of action -- the complete name is Beta adrenergic receptor agonists. Drugs have their effects on cells in two main ways: a) by getting into the cell through the cell wall and acting directly to change the machinery of the cell and b) by engaging a receptor on the cell surface - a sort of messenger on the surface of the cell that communicates the message to the inside of the cell.
Beta agonists work in the second way; they bind the beta adrenergic receptor on t...
Read the full text of How to Spot a Bronchodilatoraholic and leave a comment! Read all of Rick Frea's posts Visit Repiratory Therapy Cave , Rick Frea's personal blog
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