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Tuesday, November 24, 2009
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Advair Diskus Inhl

Drug Interactions


Generic Name: FLUTICASONE/SALMETEROL INHALATION DISK - ORAL
Pronounced: (flew-TICK-uh-sone/sal-MET-er-all)

Advair Diskus Inhl Interactions

Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medication because very serious interactions may occur:

  • natalizumab


Avoid taking MAO inhibitors (e.g., furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine) within 2 weeks before, during, and after treatment with this medication. In some cases a serious, possibly fatal drug interaction may occur.

If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting this product.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially:

  • aldesleukin
  • amphotericin B
  • other asthma drugs (e.g., quick-relief inhalers)
  • beta blockers (e.g., metoprolol, propranolol)
  • corticosteroids taken by mouth (e.g., dexamethasone, prednisone)
  • inhaled anesthetics (e.g., halothane)
  • mifepristone
  • tricyclic antidepressants (e.g., amitriptyline, nortriptyline)


Many drugs besides this product may affect the heart rhythm (QT prolongation) including dofetilide, pimozide, procainamide, amiodarone, quinidine, sotalol, macrolide antibiotics (such as erythromycin), among others. Therefore, before using fluticasone/salmeterol, report all medications you are currently using to your doctor or pharmacist.

Other medications can affect the removal of fluticasone and salmeterol from your body, thereby affecting how this medication works. These drugs include nefazodone, telithromycin, azole antifungals (such as ketoconazole, itraconazole), macrolide antibiotics (such as clarithromycin), HIV protease inhibitors (such as ritonavir, saquinavir). This is not a complete list.

Check the labels on all your medicines (e.g., cough-and-cold products, diet aids) because they may contain ingredients that could increase your heart rate or blood pressure. Ask your pharmacist about the safe use of these products.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

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