I have struggled quite a bit with substituting Q10 for Lithium. Adding to my existing dose was relatively easy, substituting was not. I think I am now stable but it is so recent I cannot be sure. I reduced my dose of Lithium from 1150 mg to 900 mg about 2 months ago (I put up a few posts at that time). Because reducing the Lithium and adding primrose oil all have destabilizing effects for 2-3 months, it is like trying to hit a moving target. The trick is to balance it against evening primrose oil which acts as a conventional antidepressant. The whole process is a bit complicated but I'd be happy to share what I know with everybody. I believe it is common practice where appropriate to combine antidepressants with mood stabilizers. I think what I am doing is a nutritional analog of that approximately. Q10 is not exactly a stabilizer though. If you are going to try this approach, I highly recommend adding Q10 and primrose oil to your regimen first and getting the hang of it. Only then attempt the reduction in stabilizer, if that is what you intend. Andrew
