Absolutely it affects us more. I went to Hawaii last year going through many time changes and long trip with no sleep. Was hypomanic the entire time in Hawaii. It took a few weeks to settle back down coming home as well. I have OCD as well and usually it is OK, when I travel ANYWHERE I obsess about every little detail before I go like "is everything packed", "are the animals going to be ok" and on and on. Once I get there I am fine. Pat