A two year trial comparing relapse rates from people taking either sodium valporate, or lithium plus valporate, has concluded the combination therapy reduces the likelihood of a bipolar relapse.
Results of the trial published in the medical journal The Lancet, suggests the more common practi...


ok... ok
let's see.... Depakote (known big weight gainer, side effects, anti-epileptic) had a try & fail rate of 69% resulting in relapse - meaning 31% had success using it
Lithium (known weight gainer, side effects, labs, and oldest & only Bipolar med) had a try & fail rate of 59% resulting in relapse - meaning 41% had success using it
big 10% point spread there
Yet... you put the 2 together and you have a try & fail rate of 54% resulting in relapse - meaning 46% had success using it
giving only 5% difference between the combo and just lithium compared to just lithium and depakote's 10% difference individually
to me... lithium still kicks depakote's butt