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Dear Susan,   I think it can be both, but in my experience the Seroquel really accelerated my weight gain with binge eating, especially at night.  And it was with carbs/sugars that I wanted.  When I first began the drug I would wake from a sound sleep -- very thirsty -- and go for the easiest thing I could eat or drink: pancake or chocolate syrup from the bottle, jelly out of the jar with a spoon, half a box of fruity pebbles, etc.   As time went by, and 45# crept on me, I lost most of those early cravings.  But now I find myself ALWAYS needing something to drink at my side.  Usually water or decaf-unsweetened iced tea.  I avoid diet sodas due to bloating and side effects of artificial sweeteners.  And I had to re-train myself to like non-carb food again.   I haven't lost too much weight since then, but I'm not gaining any more now.  I was tested for diabetes, since these atypical antipsychotics are known to cause metabolism changes, and this may be something you should look out for.   A final note-- we always hear about exercising.  I agree 100%  And I would love to give all exercise trainers a bipolar cocktail and tell them to "get some exercise".   OK, so stretch several times a day.  Do it enough that it makes you feel warmer.  Practice good posture.  Rid your home of junk food.  Binge on scrambled eggs.  Drink a ton of fluid because SEROQUEL IS MAKING YOU THIRSTY!   Good luck. Angie