Geodon Oral

Geodon Oral Interactions

Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medications because very serious interactions may occur:

• sibutramine
• drugs which may affect the heart rhythm (QTc prolonging drugs such as amiodarone, dofetilide, pimozide, procainamide, quinidine, sotalol, sparfloxacin, and thioridazine, among others)

If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting ziprasidone.

QTc prolongation can infrequently result in serious, rarely fatal irregular heartbeat. Consult your doctor or pharmacist for details and a more complete list of medications. Ask for instructions about whether you need to stop any other QTc-prolonging drugs in order to minimize the risk of this effect.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

• antimuscarinics (e.g., scopolamine)
• drugs for high blood pressure (e.g., beta blockers, calcium channel blockers)
• dopamine agonists (e.g., amantadine, bromocriptine)
• levodopa
• "water pills" (e.g., furosemide, hydrochlorothiazide)
• drugs affecting liver enzymes that remove ziprasidone from your body (such as azole antifungals including ketoconazole, macrolide antibiotics including erythromycin, rifamycins including rifampin, St. John's wort, certain anti-seizure medications such as carbamazepine)

Also report the use of drugs which might increase seizure risk (decrease seizure threshold) when combined with ziprasidone such as bupropion, isoniazid (INH), phenothiazines (e.g., chlorpromazine), theophylline, or tricyclic antidepressants (e.g., amoxapine) among others. Consult your doctor or pharmacist for details.