Chemo Regimen FAQs: CAF or FAC Chemotherapy

Q. OK, here's the $64,000 question: what are the side effects of CAF?

A. Remember, as you read this, that it's an overview: not every woman gets every side effect. In fact, probably no one gets every side effect, and many women experience very few. Here are the highlights... er, lowlights of what you MIGHT experience:

• Nausea/vomiting/diarrhea: All three of these are a possibility. The good news is, this unpleasant side effect is much, MUCH better controlled than it used to be, via medication. So don't listen to anyone's awful stores about when they had chemo five years ago and how sick they were! TIMES HAVE CHANGED.

You'll probably get some anti-nausea drugs right along with your treatment, plus some to take home, just in case. If you feel nauseous, and you've taken your medication, don't suffer in silence! Call the doctor and get a prescription for something else. There are all kinds of anti-nausea drugs they can try; it's not one-size-fits-all. They'll keep trying till they find what works best for you.

• Hair loss: Sorry. No two ways about it, you'll lose some or all of your hair due to CAF treatment. This will probably happen 1 1/2 to 2 weeks after your first injection (though this isn't a hard and fast schedule; some women lose their hair a bit later). Prepare by deciding on a wig, head gear, or if you're simply going to "go naked." It also helps to cut your hair short before it falls out. Somehow, going from short hair to no hair is easier than long hair to bald.

• Increased risk of infection: You'll be losing white blood cells; the drugs will destroy some of them, along with the cancer cells. You'll be at your most susceptible starting midway through each cycle, and extending to the next treatment.

What can you do about this? The usual things you do all winter to prevent a cold; avoid crowds, wash your hands often, stay away from people who are sick. Remember, an infection you get now will be more serious than a cold, so use your common sense. Don't put yourself at unnecessary risk.

• Unpleasant taste in your mouth: Have you heard anyone mention "tin-can mouth"? You may develop a metallic taste in your mouth; not much you can do about this one. Don't eat spicy foods in an attempt to "drown out" the metallic taste; it won't work, and may give you mouth sores. Speaking of...

• Mouth and throat sores: These feel like a series of cold sores inside your mouth and partway down your throat. Obviously, it makes eating a pain-literally. Try chewing on ice chips the first 5 to 10 minutes of each treatment; some women have reported success with this method of preventing sores. If sores develop, ask for medication from your doctor. They have stuff that can help. Oh, and don't use harsh mouthwash or eat spicy foods when you have mouth sores; either of those will exacerbate the situation.

• Fatigue: As you advance through treatment, you'll probably find yourself feeling more and more tired. This fatigue can range from mild (increased difficulty climbing stairs) to major (staying in bed all day). Try some gentle exercise, no matter how bad you feel; even walking helps. And eat enough to keep your strength up. Not eating and not exercising make you feel tired even when you're not undergoing chemo, so going hungry and being inactive exacerbate chemo's fatigue even more.