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Kevin Knopf, MD

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Medical Oncologist

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posted 05/12/2008, comment (1)

Tamoxifen Breakdown Gene CYP2D6 - Is the Plot Thickening?

I wrote about CYP2D6, which refers to a gene that codes for a biologic molecule involved in the breakdown of tamoxifen, about a year ago. Since then it has not become standard of care to order this on patients taking tamoxifen, but my desire to do so has increased. Routine testing is not yet recommended, according to those in the... Read more Chevron

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Kevin Knopf, MD

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Medical Oncologist

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posted 11/29/2006, comments (2)

Something to Worry About? CYP2D6 and Tamoxifen/Nolvadex Effectiveness

Tamoxifen (Nolvadex) Effectiveness: Something to worry about?Over my morning coffee and one of the three daily newspapers I read I see a note “Panel seeks Cancer-Drug Warning” hot off the AP wire. Here's a link to other outlets that reported on it.It turns out that an FDA panel wants to warn women on tamoxifen (nolvadex) that there... Read more Chevron

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