Breast Cancer - All SharePosts Relating To "her2"

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Kevin Knopf, MD

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Medical Oncologist

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posted 03/18/2009, comments (4)

When Even the Experts Disagree…Who Benefits from Adjuvant Chemotherapy

Data presented at the San Antonio Breast Cancer Symposium show that basically all women with HER2+ breast cancers benefit from adjuvant chemotherapy/Herceptin due to their worse prognosis. In my mind, however, there is no more controversial area in breast cancer than in which patients truly benefit from receiving adjuvant chemotherapy, among women... Read more Chevron

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Kevin Knopf, MD

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posted 03/10/2009, comments (0)

Chromosome 17 Copy Predicts Response to Anthracyclines (Doxorubicin)

After much debate at breast tumor boards throughout the world on the importance of HER2 and topoisomerase II (an enzyme involved in DNA replication) in predicting response to Anthracyclines, it seems that an extra copy of chromosome 17 in the cancer may be predictive. Things change pretty quickly. We typically don't analyze chromosome 17... Read more Chevron

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Kevin Knopf, MD

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posted 02/09/2009, comments (0)

All HER2 Positive Breast Cancers Should Get Adjuvant Chemotherapy and Herceptin

From the San Antonio Breast Conference in December, new data shows a higher than predicted rate of breast cancer recurrence even with very small breast cancers that are HER2 positive. The data is from the first large study to analyze early-stage breast cancer patients with HER2 positive tumors one centimeter or smaller. All these women would... Read more Chevron

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PJ Hamel

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posted 12/15/2008, comments (25)

Reading The Pathology Report - A Layperson’s Guide To Understanding Your Breast Cancer Diagnosis

“Have you got your pathology report yet?”As a woman newly diagnosed with breast cancer, it seems that everything hinges on this all-important document. Will you have chemo? Is a lumpectomy “good enough?” And how about those hormone drugs: yes, or no? Here's an example of what your pathology report might look... Read more Chevron

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Kevin Knopf, MD

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posted 11/07/2008, comment (1)

What is Personalized Medicine for Breast Cancer?

Personalized medicine actually has two meanings. The first, and probably the one most familiar to us in San Francisco, is the trend to have "concierge" style medicine - usually an internist, family practitioner, or Ob/Gyn who takes a panel of patients for a set fee per patient, rather than taking insurance. This is a prominent phenomena in many... Read more Chevron

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